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FINGOLIMOD HYDROCHLORIDE
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DeCS
Descriptor
English
:
Fingolimod Hydrochloride
Descriptor
Spanish
:
Clorhidrato de Fingolimod
Descriptor
Portuguese
:
Cloridrato de Fingolimode
Tree Number:
D02.033.100.700.350
D02.033.455.706.431
D02.092.063.700.350
Definition
English
:
A sphingosine-derivative and IMMUNOSUPPRESSIVE AGENT that blocks the
migration
and homing of
LYMPHOCYTES
to the
CENTRAL NERVOUS SYSTEM
through its action on
SPHINGOSINE
1-PHOSPHATE RECEPTORS. It is used in the treatment of
MULTIPLE SCLEROSIS.
History Note
English
:
2016 (1996)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
55866
Unique Identifier:
D000068876
Occurrence in VHL
:
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